Firma:              Waters

Modell:                         996

Kommentar:     Dokumente engl.

Obtaining complete spectral data no longer means compromising chromatographic sensitivity. The 996 PDA Detector has the chromatographic sensitivity of even the best tunable UV/Vis wave­length detector. Trace amounts of sample and minor impurities can be detected and quantitated accurately.

Advanced optics enhances sensitivity und detectability

Optical design innovations enable the use of 10 mm flow cells to provide a 67% increase in observed absorbance over PDA detectors with 6 mm flow cells.

The 996 PDA Detector flow cell features the patented Toper-Beam technology that reduces refractive index effects at the eluate/flow cell interface. This technology focuses maximum light intensity on the diode array and improves detectability by reducing noise resulting in improved sensitivity. What's more, advanced mathematical algorithms for the 996 detector improve detection by reducing baseline noise (Figure 5B).

Lamp optimization software maintains high signal-to-noise ratio

Reducing baseline noise is a key element in maximizing compound detection. To ensure consistent performance over time, special software unique to the 996 PDA detector automatically maintains a minimal noise level over the lifetime of the lamp The software selects an appropriate exposure time for the diodes based on lamp energy, mobile phase and wavelength-range. This optimization, automatically performed before each injection, requires no manual adjustments to the detector operating current, slit width, or diode resolution.

Waters 996 Photodiode Array Detector Gives You Confidence - Erases the Doubts.

You're developing an HPLC method for analyzing the composition of a high-value-added fine chemi­cal. You're responsible for developing methods to check for impurities in a drug to treat hypertension. You ve been given the task of isolating a compound taken from a rare plant that is known for its curative powers.

With challenges like this, you may have to place your reputation and that of your lab at stake. Can you afford not to invest in technology that gives you confidence in your ability to deliver results that are the best they can be?

How do I know if this substance is really pure or isn't something else?

With Waters 996 Photodiode Array Detector, you can be confident that if there is an impurity in your sample, you'll find it; that your compound is really what you report it to be and not something else. Every spectral detail of your sample is rapidly, easily, and accurately detected. Every peak is analyzed with mathematical precision so you can be sure your ability to assess the purity of peaks and confirm their identity is state-of-the art. And you will never have to trade off resolution for sensitivity.

Confidence in results through technological innovation

The 996 Photodiode Array Detector represents the most powerful combination of software and optics uniquely integrated to provide speed, detectability, and ease-of-use. Built into the 996 PDA Detector are technological innovations for obtaining the most complete and accurate spectral data of any photodiode array detector available today - designed to greatly enhance your ability to do more with the time you have and give you more confidence in the integrity of your results.

• Absorbance measurement over the entire 190-800nm wavelength range (or for any pre-selected wavelength range) to-obtain as detailed a spectral map as possible.

• Powerful Millennium ^® software routines with advanced mathematical algorithms give you the rare ability to see the finest spectral details of even trace analytes. With Millennium Software you can extract wavelengths, calibrate, quantitate, determine peak purity, perform library com­parisons, check system suitability, calculate RSD's, print custom reports and export all data automatically and without time consuming, post-run, manual calculations.

• Advanced Taper-Beam optics for exceptional signal-to-noise performance and the linearity you need to analyze major peaks and minor impurities in the same run.

Validation and quality begin with our ISO 9000-certified manufacturing process

To assure product quality, reliability, und consis­tency, Waters instruments, data management sys­tems und chemical products are developed and manufactured in accordance with Waters Total Quality Management (TQM) programs. Manufacturing operations are defined by written SOP's und specifications und are cerfified to ISO 9000 International Quality Management Standards und comply with cGMP requirements, Certificates of Validation are supplied with most products to verify that product design has been validated using a System Development Life Cycle (SDLC) process.

From installation to scheduled maintenance, Waters expertise in compliance und quality management is available to assist you in meeting ISO 9000 and regulatory requirements.

Qualification workbooks from Waters form the foun­dation for your Laboratory Validation Master Plan. Module and system level SOP's (IQ, OQ, PQ) guide you through installation, operation and main­tenance for both instrument und data products.

Specially trained and certified Validation Support Specialists are available to assist you by providing maintenance and qualification services.

Optional Preventative Maintenance und Total Protection Service Plan coverage can be enhanced to include qualification services.

Operating Specifications

Wavelength range                            190-800 nm

Light source                                      Deuterium arc lamp

Spectral resolution                            1.2 nm per photodiode (digital and optical)

Wavelength accuracy                       ± 1 nm

Linearity range                                  5% over-0.1 to 2.0 AU

                                                         Propyl paraben, 257nm

Baseline Noise                                  ±1.5 X 10 ⁵ AU at 254 nm (10mm cell)

Drift                                                   <1 X 10 ³ AU/hour at 254 nm

Sensitivity setting range                    0.0001-2.0 AUFS (under software control)

Taper Beam flow cells                      Cell Pathlength/volume

                                                         Standard analytical       10 mm/ 8 µl

                                                         Semi preparative          3 mm/2.5 µl

                                                         Inert                               10 mm/8 µl

                                                         High pressure               10 mm/8 µl

                                                         Microbore                      3 mm/2.5 µl

Outputs                                             Two analog integrator outputs

                                                         Two programmable event outputs

Physical/Environmental Specifications

Dimensions                                      Width:11,5 inches (29 cm)

                                                         Height: 5;9 inches (15 cm)

                                                         Depth: 22 inches (56 cm)

Weight                                              34 lb. (15,4 kg)

Temperature                                     Operating: 4 to 40°C (39 to 104°F)

Humidity                                            Operating: 20 to 80%, non-condensing programmable         lamp shutoff

Electrical Specifications/Requirements

Power requirements                         115 VAC (90-132 V), 50/60 Hz

                                                         230 VAC (190-264 V), 50/60 Hz

Power consumption                         100 VAC (nominal)