manufacturer :      Corning

model :                   LFR Microreaktor

annotation :           Dokumente engl .

The temperature management within the Corning reactors is ensured by a circulation of heat exchange fluid(s) within the heat exchange circuit(s) of the reactors. These fluids are provided by the customer. The source may be thermostats or plant circuits.

Corning Recommendations

In addition to the Boundary Conditions defined (Annex 1), and which must be respected at all times, please consider the following to improve performance:

- A minimum flow rate in the Fluidic Modules heat exchange (HE) path of 100 mL /min to get the nominal heat exchange coefficient. Recommended operation if the best thermal inertia is targeted is to operate at HE flow as high as possible; for 0.7bar this is around 250 ml/min for reactor A and 350 ml/min for reactor B.

- Choose a chiller with external regulation by placing a PT100 thermal couple (TC) at the entrance of the heat exchange path. This way, the power will be regulated based on the temperature at the entrance of the heat exchange circuit and not in the chiller . This will suppress the temperature decrease between the chiller and the reactor.

- Fluid: Don’t feed suspensions or solids. Use a filter (10-30 micron) before the pumps or filter the solutions before injection in order to avoid particles.

- Chemical compatibility with glass, Chemraz , PFA: Check reactor materials for your specific case.

- Temperature: Don’t set temperature close to the reaction fluids freezing points.

Thermostat Selection

The selection of the appropriate thermostat and heat exchange fluid is important in order to be within the recommendations provided and get performance from the reactor.

The following thermostat specifications must be considered:

Operating temperature range

The process temperature has to be within the operating temperature range of the thermostat with a 5°C margin.

Cooling power

The cooling power provided by the thermostat must be higher than the following sum:

P reaction (W) + [10 W * Number of Fluidic Modules connected to this specific thermostat] +

Pconnect (W)

P reaction is the power released by the reaction within the reactor.

10 W is the margin to incorporate for maximum thermal losses in the reactor.

Pconnect is the thermal losses in the connection between the thermostat and the reactor

heat exchange inlet .