Quantify with exceptional accuracy using the Thermo Scientific TSQ Quantum Ultra Triple Quadrupole Mass Spectrometer. Achieve excellent sensitivity and specificity without sacrificing versatility. The TSQ Quantum Ultra system is optionally available with Extended Mass Range (EMR), Accurate Mass (AM), and High Field Asymmetry Ion Mobility Spectrometry (FAIMS) to meet the needs of a wide range of applications. Specifications:. Sensitivity. Electrospray (HESI) at high resolution of 0.2 Da FWHM: A 5 µL injection of a 200 fg/µL reserpine solution on a Hypersil GOLD aQ 20 x 2.1 mm, 1.9 µm particle packed column at a flow rate of 300 µl/min 30:70:0.02 water/methanol/formic acid produces a minimum signal-to-noise ratio of 3000:1 for the transition of the protonated molecule at m/z 609.3 to the fragment ion at m/z 195, 1 in Selected Reaction Monitoring (SRM) mode, with the resolution for Q1 and Q3 set to 0.2 and 0.7 Da FWHM, respectively. Atmospheric pressure chemical ionization (APCI) and atmospheric pressure photoionization (APPI) at high resolution of 0.2 Da FWHM: A 5 µL injection of a 200 fg/µL reserpine solution as described above produces a minimum signal-to-noise ratio of 300:1. Mass Accuracy – TSQ Quantum Ultra AM. Infusion of a mixture of polyethylene glycols (PEGs) with average molecular weights of 200, 400, 600, and 1000 at 50 pmoles/µL produces 27 ammonated PEG ions ranging from 124 to 1268 Da. Exact masses are generated for each of the 25 ions from 168 to 1224 Da using adjacent peaks as internal lock masses. The mass of each ion is determined from the average of up to 100 scans, and the error between the expected mass and the measured mass is expressed in mmu and ppm. The root mean square (RMS) average is calculated from the errors of the 25 individual ions. The RMS error is less than or equal to 5 ppm. Mass range. 10 to 1500 Da (TSQ Quantum Ultra/Ultra AM). 10 to 3000 Da (TSQ Quantum Ultra EMR). Resolution. 7500 (FWHM) at m/z 508 from polytyrosine. The resolution can be continuously adjusted to better than 0.1 Da peak width (FWHM) over the entire mass range. Mass stability. The laboratory room temperature must be maintained between 15-27°C (59-81°F). The optimal operating temperature is between 18-21°C (65-70°F). TSQ Quantum Ultra/Ultra EMR. The mass assignment is ±0.050 Da within a 24-hour period. The room temperature must not fluctuate by more than 5°C (9°F) during this period. TSQ Quantum Ultra AM. The mass assignment is ±0.025 Da within a 24-hour period. The rate of change of temperature must not be more than 2°C per hour (3.6°F/hr) and not more than 5°C (9°F) during this period. Labprocure is responsible for this device.